Ipamorelin is a synthetic peptide that belongs to a class of compounds known as Growth Hormone Secretagogues (GHSs). It is a pentapeptide that stimulates the release of growth hormone (GH) in the body. Ipamorelin is a newer GHS than others, such as GHRP-6 and Hexarelin, and is considered a more selective and specific agonist of the GH-releasing hormone (GHRH) receptor, resulting in a more targeted release of GH.
What is Ipamorelin?
Ipamorelin is a synthetic peptide composed of five amino acids. It is a growth hormone secretagogue which stimulates the release of growth hormones in the body. Ipamorelin is unique among GHSs in that it is a selective and specific agonist of the GHRH receptor, resulting in a targeted release of GH.
How does Ipamorelin work?
Ipamorelin works by binding to the GHRH receptor in the hypothalamus and pituitary gland, which leads to the release of growth hormones. Unlike other GHSs that often result in the release of other hormones, such as cortisol and prolactin, Ipamorelin is considered a more selective agonist of the GHRH receptor, resulting in a more targeted release of GH. This can help to promote muscle growth and repair, as well as to enhance fat loss and improve overall body composition.
What are the potential benefits of Ipamorelin?
The potential benefits of Ipamorelin include increased muscle growth and repair, enhanced fat loss, and improved overall body composition. Additionally, Ipamorelin may help treat conditions such as growth hormone deficiency and muscle wasting diseases. Ipamorelin has also been used as an anti-ageing therapy, as well as to improve sleep, skin health, and overall well-being.
What are the potential side effects of Ipamorelin?
Ipamorelin is generally considered to be safe and well-tolerated when used as directed. However, some people may experience side effects such as headaches, muscle pain, and water retention. Additionally, long-term use and high dosages of Ipamorelin may lead to an increase in growth hormone levels.
Research Dosage:
In human trials, the dosage of Ipamorelin has varied depending on the specific study and the research goals. The dosages used in human studies have ranged from 100mcg to 300mcg per administration.

References:
- Ipamorelin. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK56962/
- Ipamorelin. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/24681757
- Ipamorelin. (n.d.). Retrieved from https://www.uniprot.org/uniprot/P49327